Yassin, Saif Almazrouei, Dana Aldhaheri, Mahra Alderei, Shamsa BaniYas, Shamsa H
634 AAK1 inhibitor LX-9211: Junctional protein 2-associated kinase 1 (AAK1) is widely expressed in the brain and spinal cord and is a viable target for the treatment of neuropathic pain, and BMS-986176/LX-9211 is a novel class of bis(iso)aryl ethers that are highly selective, CNS-permeable, and potent AAK1 inhibitors
He and his colleagues confirmed that the extra glutathione in the treated mice caused levels of RhoA to increase in their metastatic tumors
He has co-authored 3 textbooks with 15 National and International Publications to his name
Unlike GLP-1 medications, gastroparesis is more severe and can cause serious symptoms
These symptoms generally improve by week 10-12 as the body adapts to maintenance dosing