Start at the lower end of your weight-based dose and build up across sessions to dial in your personal sweet spot
The key distinction is that Wegovy is formulated at a higher dose to achieve the robust weightloss effect that the FDA approved it for, whereas Ozempics dosing is optimized for glycemic control (type-2 diabetes)
Diabetes 60 , 23152324 (2011)
In the case of GLP-1s, that decision is a long-term commitment
In brief, berberine can reduce anti-apoptotic factors (Bax/bcl-2, caspase), autophagy related proteins (IL-3, Beclin, etc.), A pathology, and activate PI3K-AKT and other signaling pathways, and then produce neuroprotective effect (Figure 1)
Even Chepngenos case comes with some caveats, in my view