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Because GLP-2 acts through subepithelial myofibroblasts, which are the same cell population implicated in intestinal fibrogenesis, the risk-benefit profile of GLP-2 agonism may differ substantially between mucosal UC, inflammatory ileal CD, and stricturing or penetrating CD phenotypes, and this phenotypic stratification should be a required feature of future trial design
With BioNeMo running on Roches Blackwell GPUs, scientists can train or fine-tune large language models (LLMs) or diffusion models on protein/genomics/compound data
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Once a niche topic in endocrinology, this naturally occurring gut hormone has been thrust into the global spotlight, heralded as a revolutionary tool in the management of type 2 diabetes and, most notably, weight loss
Inhibition of the electron transport chain in propofol induced neurotoxicity in zebrafish embryos
Cerovecki T et al
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