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Gastrointestinal lining research Interest in its origins as a gastric peptide fragment
One study observed that in mice with demyelinating injury, liraglutide promoted the proliferation and maturation of oligodendrocyte precursor cells, activated the p-AMPK/SIRT1 signaling pathway, enhanced autophagy, and inhibited neuroinflammatory responses
Evidence suggests that GLP-1s are not only effective in preventing the accumulation of amyloid beta, a protein commonly associated with Alzheimer's, but also in mitigating the hyperphosphorylation and aggregation of tau, another critical protein in the disease's progression