Its not always possible to know how a certain medication will affect your body on its own, let alone with other medications thrown into the mix
Pfeffer MA, Claggett B, Diaz R, Dickstein K, Gerstein HC, Kober LV, Lawson FC, Ping L, Wei X, Lewis EF, Maggioni AP, McMurray JJ, Probstfield JL, Riddle MC, Solomon SD, Tardif JC
Studies have shown that people continue losing weight on a GLP-1 RA for a year or even longer
Expect to commit to regular application for minimum three months before evaluating effectiveness
Circulation 106 , 653658 (2002)
Also, comparatively high insurance coverage in the US albeit with requirements concerning prior authorization, offers coverage to 70-80% of patients with conditions that allow GLP-1 therapy with out-of-pocket costs that are manageable, unlike in less price-sensitive international markets