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Some effects, like feeling fuller after a high-fibre or high-protein meal, can be noticeable fairly quickly
This has been evaluated in the STEP-HFpEF (people with obesity and HFpEF without diabetes) and STEP-HFpEF DM (people with obesity and HFpEF with T2D) trials 44
Vomiting more than once per week
Huang M, Wei R, Wang Y, Su T, Li Q, Yang X, Chen X
Reshmi Srinath, director of the Weight and Metabolism Management Program at NYU Langone Health, emphasizes that there is no rigorous scientific evidence supporting microdosing approaches