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Naltrexone, approved in 1984, introduced a non-opioid antagonist that blocked the effects of opioids but required full detoxification before initiation, limiting its early use
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doi: 10.3168/jds.2015-10054 47
2b, f) from 11.6 1.5% ( n = 3 hearts) to 73.9 9.0% ( n = 6, p = 0.0001, one-way ANOVA with Tukeys test)
Some studies have also indicated potential roles in cartilage regeneration and immune-related pathways
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