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Key findings In an eight-week randomized, double-blind, placebo-controlled trial involving 50 adults seeking treatment for moderate-to-severe AUD, participants receiving oral semaglutide showed: Fewer heavy drinking days Reduced alcohol consumption per drinking occasion Lower day-to-day alcohol cravings Fewer alcohol-related problems Improved overall drinking risk level Reduced cannabis use days While not all measures changed in controlled laboratory settings, the overall pattern showed consistent reductions in harmful real-world drinking behavior

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Key Background Musks push for affordable GLP-1 medications comes as lawmakers on both sides have sought expanded coverage for weight loss drugs

Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy