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Whilst previous studies have largely focused on non-biodegradable MPs [33], our study provides the first systematic evidence that biodegradable PBAT-MPs impair neurological function through the gutbrain axis, and further identifies microglial lipotoxicity as a critical downstream mechanism

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CJC-1295 acts as a GHRH analog and stimulates growth hormone production, while Ipamorelin (acting as a ghrelin mimetic / GHRP) binds to ghrelin receptors, thereby suppressing somatostatinthe hormone responsible for inhibiting growth hormone release

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