Proximal injection near the injury site is preferred for musculoskeletal applications because it appears to increase local tissue concentration
Some act mainly through the GLP-1 receptor
According to the SURMOUNT-5 trial published in May 2025, participants on the maximum tolerated dose of Semaglutide (1.7 mg or 2.4 mg) achieved an average weight loss of 13.7% over 72 weeks
was supported by the Ministerium fr Kultur und Wissenschaft des Landes Nordrhein-Westfalen, Senatsverwaltung fr Wissenschaft, Gesundheit und Pflege Berlin, and by the Bundesministerium fr Bildung und Forschung (BMBF) (for F.-L.H, J.D., E.T., K.L., S.H.)
24 , R453R462 (2014)
Semaglutide (marketed under the brand name Wegovy) and liraglutide (Saxenda) did lead to weight loss, but it was significantly less at 15% and 8%, respectively