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The C-terminal domain contributes, together with the N-terminal domain, to shaping the co-substrate binding site, which is termed H-site, from the hydrophobic nature of co-substrates

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On day 3, 3 10 T cells isolated from a healthy donors PBMCs were administered to three groups of mice: IL1RAPCD3 with T cells, IL1RAPCD3null (non-CD3-binding control) with T cells, and T cells alone

10.1111/j.1651-2227.2005.tb02097.x Acta Paediatrica

Targeting the diet-microbiota-barrier axis therefore represents a promising therapeutic strategy for chronic inflammatory disorders (140, 141)

[PMID: 3074794] PubMed record related to this compound for laboratory literature review