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The most commonly reported side effects include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, which occur in a substantial proportion of patients, particularly during dose escalation

This process is called dose titration

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How GLP-1 Receptor Agonists Work GLP-1 receptor agonists like semaglutide work by: Increasing Insulin Secretion: When blood sugar levels are high, semaglutide stimulates the pancreas to release more insulin, which helps lower blood sugar

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