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If you have any of those, the risk calculation changes significantly
Adequate water intake (2.53 litres daily, more in summer) helps your body process metabolites efficiently and reduces the chance of headaches
however, more recent trials have been unable to clearly corroborate these findings
A separate 2025 narrative review flagged theoretical concerns about pathologic new blood vessel formation, which is the basis for the cancer-history caution below
Meanwhile, out-of-pocket costs for these medications are not likely sustainable for most patients
Johannes F
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