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Notably, treatment cohorts in RCTs typically report more pronounced effects than controls for the primary outcomes we assessed, and in our real-world study, there was a clear continuum of responsiveness to GLP-1s, suggesting a high degree of variation in terms of patient benefit from GLP-1s

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For patients travelling to Chiang Mai for treatment, that process also provides reassurance that decisions are being made within a clinical setting rather than relying on information gathered from forums, social media, or anonymous online reviews

Science 369 , 11191123 (2020)