Moreover, mice with neutrophil-specific Gpx4 haploinsufficiency develop lupus phenotype and inhibition of neutrophil ferroptosis significantly mitigates disease development in lupus-prone mice
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However, cBMAT adipocytes are resistant to conventional lipolytic cues such as acute fasting, caloric restriction, exercise, -adrenergic agonists and cold exposure 2,3,5,6,7,11,12,13
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Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis