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It is essential to rule out clinically significant conditions such as Coeliac disease, Inflammatory Bowel Disease (IBD), or other gastrointestinal pathologies
The Committees recommendation will inevitably be interpreted by many as an endorsement of broader clinical use
Patients with pernicious anaemia or complete malabsorption typically require lifelong treatment at standard intervals, while those with partial malabsorption may have variable needs
In general, B12 is available in a high concentration, so most injections are a low volume, and they are administered every one to two weeks as needed
Comprehensive medical assessment before initiating treatment remains essential, as clinical trial populations never fully represent the diversity of health conditions encountered in practice
