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Some individuals report that their hunger signals remain low enough to skip meals without discomfort, while others describe food simply becoming less interesting or rewarding

Neuroscience Research 37 (3): 227-36

As such, the effect of GLP-1RAs on DR should be viewed with caution

However, if youre already on the maximum dose of semaglutide (2.4 mg) and your weight loss has stalled for more than a month, consider talking to your provider about switching to tirzepatide

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