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NICE guidance prioritises SGLT2 inhibitors for those with established or high risk of cardiovascular or kidney disease, with GLP-1 receptor agonists as add-on or alternative therapy where appropriate

Recommendations are based on factors such as medical history, current medications, clinical findings, and provider judgment

For calculation and normalization of the probes oxidation degree at each time point, the means of all values recorded at all time points for R red , R ox , I 488 ox and I 488 red were used

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For context, Wegovy costs approximately $1,350 per month at list price

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