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Consistent with their high de novo ser/gly synthesis, 2012.2 cells showed the preference for incorporating glucose-derived serine and glycine into the synthesis of purine and pyrimidine nucleotides, i.e., ATP, GTP, CTP, UTP, TTP, reflected as m + 6 to m + 9 labeled nucleotides (Fig

Another study demonstrated a remarkable 42% reduction in glucose area under the curve and a 40% reduction in insulin area under the curve compared to placebo

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