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In contrast, those switched to a placebo regained 6.9%

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Lastly, vagal receptors can detect regulatory gut peptides, inflammatory molecules, dietary elements, and bacterial metabolites to relay signals to the CNS via direct neural signaling (410), but there is also some evidence for direct activation of neurons by the gut microbiota

[PMID: 15644865] PubMed record related to this compound for laboratory literature review