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Current evidence suggests GLP-1 medications improve fertility primarily through weight loss and metabolic improvement rather than direct reproductive effects
GLP-1 medications are approved for adults who have a body mass index (BMI) of 30 or higher, or a BMI of at least 27 plus a weight-related medical condition, such as the following: Type 2 diabetes High blood pressure High cholesterol Obstructive sleep apnea Cardiovascular disease that increases the risk of heart attack or stroke MASH, or metabolic dysfunctionassociated steatohepatitis, a form of liver inflammation Avlin Imaeda, MD, PhD, a Yale Medicine gastroenterologist who is board-certified in obesity medicine, notes that qualifying for the medication based on heart disease aloneoften necessary for insurance coveragecan be challenging
Kanashiro-Takeuchi, R
Retatrutide is still undergoing its phase 3 trial
Systemic administration of semaglutide conferred discernible vasoprotective and anti-neuroinflammatory benefits in a rodent model of glaucoma, primarily manifesting as attenuated intraocular pressure elevation and suppression of pathological astrocyte activation and vascular remodeling
., Olorunfemi, G
