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Non-cirrhotic metabolic dysfunctionassociated steatohepatitis (MASH) with moderate to advanced liver fibrosis maintenance dose: 2.4 mg injected once weekly

The trial also showed that GI side effects were "mostly mild to moderate in severity" and were "partially mitigated with a lower starting dose." This means that many of the side effects people try to manage through timing can also be addressed through dose adjustment

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However, existing methods have only been developed for Rasch models, which assume that all the items are equal at distinguishing between individuals with different levels of the latent construct

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