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Rivus Pharmaceuticals Sector: Oral muscle-sparing therapeutics for obesity and metabolic liver disease HQ: Charlottesville, VA Year Founded: 2019 Origin Story: Rivus Pharmaceuticals was founded around the science of mitochondrial uncoupling, a natural process by which the body dissipates energy by burning fat and sugar without the muscle loss associated with caloric restriction or appetite-suppressing drugs

It becomes even more important for practitioners to be careful about who should and should not be prescribed these medications, said Naval Vikram, a diabetologist and professor in the department of medicine of the All India Institute of Medical Sciences in New Delhi

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In: NEJM: 26.06.2023,

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A study of 185,066 people with type 2 diabetes found that those taking a GLP-1 receptor agonist had a slightly higher risk of developing diabetic retinopathy but a lower likelihood of serious complications such as vision loss ( JAMA Network Open , Aug