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Marketers must manage expectations carefully and avoid overpromising

For example, in the SURMOUNT-4 trial, tirzepatide discontinuers were randomized to a placebo, and they were unaware whether they were receiving tirzepatide or not. In real-world settings, the most common reasons for discontinuation are cost or insurance-related issues, and side effects, with the former predominating, he added

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Agrati C, Sacchi A, Bordoni V, Cimini E, Notari S, Grassi G, et al

She also found intriguing the promise of increased mental clarity and a decreased risk of heart disease, Alzheimers, multiple sclerosis and Parkinsons