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Nevertheless, therapeutic hypothermia is only partially effective (5760), and many infants with HIE remain at substantial risk of death or severe long-term neurodevelopmental impairments (55)

Additionally, injection site reactionsincluding pain, redness, or swelling at the injection siteare documented adverse effects that should not be confused with systemic muscle pain

Dose optimization reduces long-term costs

However, clinical evidence favors GLP-1 compounds like semaglutide for sustained, superior outcomes combined with cardiovascular protection

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