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Reviewing peptide legality and current regulation news reveals that retatrutide occupies a grey zone

Unlike GHRP-2 and GHRP-6, which can elevate cortisol, prolactin, and acetylcholine levels, ipamorelin has been shown in animal studies to have no significant effect on adrenocorticotropic hormone (ACTH), cortisol, follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-stimulating hormone (TSH), or prolactin release

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However, it is difficult to separate these two aspects in the current study design

Lorenz M, Evers A, Wagner M