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However, based on animal studies with GLP-1RA related peptide polyagonists, they seem to be more effective in improving hepatic fibrosis, possibly due to the additive or synergistic effects of more than one receptor agonist

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On June 12, 2023, Merck (NYSE: MRK), known as MSD outside of the United States and Canada, announced that new findings for efinopegdutide (MK-6024), an investigational GLP-1/glucagon receptor co-agonist, have been accepted for oral presentation at the European Association for the Study of the Liver (EASL) Annual Congress from June 21-24

Some people explore additional compounds alongside tirzepatide to address specific issues

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They are required to register with the FDA and are subject to more stringent requirements and oversight than traditional compounding pharmacies