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Potential Overlap : Since both peptides promote some form of angiogenesis, there could be an overlap in signaling pathways (like the Akt-eNOS pathway)

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For comparison, tirzepatide (Mounjaro, Zepbound) has a slightly lower constipation rate at 14-17% across doses, possibly because the GIP receptor component partially counteracts GLP-1's motility effects in some patients

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