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Individuals with a history of medullary thyroid carcinoma, MEN2, or pancreatitis are typically excluded from retatrutide trials as a class-based safety precaution
Fluctuations in oestrogen, insulin, and leptin levels - all of which are sensitive to changes in body weight and metabolic health - could contribute to these menstrual changes
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If Phase 3 trials fail to replicate the Phase 2 results, or if unexpected safety issues emerge, the FDA could delay or deny approval
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It highlights the confusion here
Barry Conrad No, there'll be stuff happening
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