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Personal or family history of medullary thyroid carcinoma (MTC): As with other GLP-1 receptor agonists, caution is advised in individuals with a history of MTC or Multiple Endocrine Neoplasia syndrome type 2, due to theoretical risk associations

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According to the UN, the global population of individuals aged 65 years and above is expected to increase significantly, more than doubling from 761 million in 2021 to 1.6 billion by 2050

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Additionally, a post-hoc compiler average causal effect analysis was performed to estimate the influence of treatment adherence on outcomes

It is important to allow adequate time at each dose level before concluding that appetite suppression is insufficient