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8-12 week protocol
it does not establish that reducing to 0.5 or 1.0 mg will hold the same plateau. One milligram has direct weight-loss evidence as an assigned treatment arm in type 2 diabetes, while small uncontrolled series suggest that dose reduction or reduced-frequency dosing can sometimes hold a plateau. No trial has established a Semaglutide step-down schedule
Schedule Your Free Consultation Today About the Author Author:** Blueline Wellness Group Medical Team Medical Reviewer:** Jose Vazquez, LVN Published:** December 17, 2025 Last Updated:** December 17, 2025 Fact-Checked:** Yes Patient-Reviewed:** Yes Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice
Common side effects are usually mild and temporary
Retrieved 15 January 2024
SELECT - 20% reduction in major adverse cardiovascular events at 2.4 mg
