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Advantages of oral form over IM injection: Less nursing time on injections Less complexity of care Less discomfort/pain Less bleeding in patients who take anticoagulants Less costly according to some analyses Disadvantages of oral form over IM injection:: Greater risk of non-compliance In 1991, a survey done on Minneapolis internists led one commentary to conclude that oral vitamin B 12 replacement for pernicious anemia was one of medicines best kept secret. 18 In 1996, when the survey was repeated again in the same area, awareness and use of oral vitamin B 12 for pernicious anemia had increased substantially (019%), but the majority of doctors still remain unaware of this treatment option (61%)
Other drugs may interact with cyanocobalamin, including prescription and over-the-counter medicines, vitamins, and herbal products
Getting a B12 injection is a straightforward medical procedure
right now in Ohio
IMPORTANT: The government does not subsidize devices
Compared to placebo, B-vitamin supplementation in these older subjects also improved a measure of executive function, a secondary outcome of the trial (93)
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