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Notably, the C-terminal FAP cleavage site remains unmodified, suggesting that LY2405319 is likely susceptible to cleavage and inactivation in human serum via loss affinity for KLB ( Figure 3A )

This shows that care must be taken in interpreting blood measurements, and that ideally one would like to conduct experiments in which both intracellular and extracellular concentrations are measured

This is especially true for patients recovering from body contouring after major weight loss

This information, including any referenced scientific or clinical research, is made available for educational purposes only

ISBN 978-0-470-12309-6

Jr., Murray Stewart, T