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27 Evidence From Clinical Trials The clinical evidence supporting the use of GLP-1RAs in HF has primarily emerged from cardiovascular outcome trials (CVOTs) in patients with T2D and dedicated HF trials ( Table 1 )

Being a multifactorial disease, it is well established that the effective management of T2DM depends on targeting the ominous octet of pathophysiological abnormalities causing hyperglycemia in such patients (Fig

We need more research

doi: 10.2337/db21-1166 32 YuXChenSFunckeJBStraubLGPirroVEmontMPet al