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Future translational studies should therefore focus on demonstrating target engagement in relevant immune cell subsets

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Zhou, Q., Li, L., Sha, F., Lei, Y., Tian, X., Chen, L., Chen, Y., Liu, H., & Guo, Y

Overall, the screen revealed unexpected and opposing functional states within the Hml + immune cell populationsome promoting growth, such as Notch, upd2, and Gpat4, while others, including hh, smo, and bmm, acted as growth suppressors