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Specifically, mitochondrial complex I is believed to be the main component of mitochondria affected in PD as Complex I of the electron transport chain is left vulnerable to oxidative damage (Vali et al., 2007)
However, none of these compounds have been tested in human Alzheimer patients, and the transition from animal models to human clinical outcomes is notoriously difficult in neurodegenerative disease
One finding that stands out is the systemic nature of injectable GHK-Cus healing effects
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