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Intense interest in the TKTL1 gene, and its encoded protein, was stimulated because it was shown that the level of TKTL1 expression correlated with poor patient outcomes and metastasis in many solid tumors
In addition, CAP values were significantly reduced in ALT responders
Together these changes indicate that while fatty acid breakdown is upregulated to meet energy demands, fat synthesis via malonyl-CoA is likely reduced in gonadal tissue under starvation
Allergic Reactions: Some individuals may experience allergic reactions, including rashes and itching
doi:10.3109/08923973.2014.956752
Cancer Res 60(5):1157-61, 2000
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