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Michael Costello, chief executive of GNC, said his company saw a big opening in helping individuals taking such drugs for weight loss
Rather than being an either-or choice for most patients, metformin often serves as the foundation while a GLP-1 agonist is added if blood sugar targets are not met or if additional cardiovascular, renal, or weight benefits are needed
Dose escalation should be a clinical decision, not a self-directed one
Tadalafil has a long half-life of about 17.5 hours
GLP-1RAs have also been shown to reduce liver inflammation and fibrosis
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