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If it happens to you, its a problem. The ocular risks of GLP-1RAs While GLP-1RAs are very positive and transformative pharmaceutical agents for chronic disease management, the report states, they have been associated with exacerbation of age-related macular degeneration, progression of diabetic retinopathy, and, most seriously, NAION
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In the case of nicotine, preclinical studies showed evidence that the rewarding effects of nicotine are reduced by stimulation of GLP-1 receptors in the medial habenula, which is a brain region that mediates nicotines aversive effects [48]
Non-steroidal anti-inflammatory drugs should be avoided owing to the potential for renal and gastric injury [12]
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