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The diagnosis is ultimately clinical, supported by laboratory findings rather than defined solely by numerical thresholds

Never shake or vortex the vial , the mechanical stress from shaking can break the peptide structure and promote aggregation

Get the details about this, as well as risks from too much folic acid, in the Folic Acid section of our B Vitamin Supplements Review, which includes our Top Picks for folic acid and folate, and other B vitamins