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Clinical trials in adults with obesity or overweight (without diabetes) reported substantial average weight reductions over 72 weeks with once-weekly tirzepatide alongside lifestyle support

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"This study investigated important outcomes (hospitalisations) that are very relevant from a clinical and public health standpoint - another important strength of the study." However, more studies and trials are needed to show that these drugs are actually driving change in addictive behaviours.

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Moreover, the reduction in DCUN1D3 expression leads to an impaired antioxidant response in sleep-deprived individuals, thereby increasing their risk of cardiovascular diseases (Shah et al

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