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TRIUMPH-4 (Completed December 2025) Primary Endpoints: Weight loss (28.7% achieved) Knee osteoarthritis pain reduction (75.8% improvement) Secondary/Exploratory Endpoints (Liver): Liver enzymes (ALT, AST, GGT) Possibly liver imaging (ultrasound or MRI) in subset Not liver biopsies Expected Publication: 2026 (full results) What We'll Learn: Do liver enzymes normalize with 28.7% weight loss in larger population
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The weekly injection acts on three hormone pathways, GLP-1, GIP and glucagon
The sensitivity analysis showed that the results were robust
Reduces oxidative stress and inflammation caused by mold toxicity
Muscle acts as your bodys engine for burning calories and managing blood sugar, says Kashyap
