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Potential explanations include differences in the type of patients included, adherence to study treatment, sample size, duration of drug exposure, and GLP1 receptor activation with greater HbA1c reduction with longer-acting human GLP1-based analogs than with some short-acting exendin-4 analogs
Following full-text review, three reports were excluded for the following reasons: no relevant outcomes ( n = 1), conference poster ( n = 1), and secondary analysis of already included studies ( n = 1)
Manter, D
doi: 10.3389/fendo.2021.732255
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Wegovy (for weight management) uses a higher maintenance dose
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