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Prescription drugs for obesity are gaining attention as lifestyle changes alone often fall short

Its called a triple agonist because it acts on three hormones: GLP-1, GIP and glucagon

Of note, exendin-phe1 acted as a competitive antagonist against the -arrestin response to GLP-1 itself, suggesting that it might reduce the in vivo -arrestin recruitment by endogenous GLP-1 (Supplementary Fig

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These medications have proven to be effective tools for patients struggling with obesity or overweight, particularly for those who also face weight-related health challenges