The conversation shifted once the data from tirzepatide's studies, especially the SURMOUNT series, was released
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However, with the advent of NuSH therapies that offer pleiotropic effects, a multi-organ or systemic approach may prove more practical
This is the point where most clinicians evaluate whether to continue, switch approaches, or cycle off
However, a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 remains a contraindication to GLP-1 RA therapy
Flowchart from BSH Cobalamin and Folate Guidelines stichtingb12tekort.nl/weten