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Neurological Function Score (Modified Longa System) Neurological deficits were evaluated 1 hour after ET-1 injection using the modified Longa scoring system: 0: No observable neurological deficit (excluded from analysis) 1: Failure to fully extend the left forepaw 2: Consistent circling to the left 3: Falling or leaning to the left side when ambulating 4: No spontaneous movement (severe infarction) Animals scoring between 1 and 3 were considered to have moderate ischemic deficits and were included in further analyses

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GLUTATHIONE DEFICIENCY Glutathione, IN GENERAL, appears to be reduced in the elderly when compared to youthful controls, even if there are no apparent disease states

The desired biological response dictates the concentration and frequency

However, the daily injection schedule may be inconvenient for those seeking general anti-aging benefits

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