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Additionally, if OCSCs are exposed to inflammatory mediators, undergo mesenchymal endothelial transformation, or experience dysregulation of the redox balance in the tumor microenvironment (TME), they may stimulate the continuous proliferation of OCSCs, potentially leading to OC development (63)
A few studies have been done addressing the above issue (Table 2) [51,52,53]
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Understanding Pigmentation: The Root Cause Pigmentation occurs due to excess production of melanin, the pigment responsible for skin color
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