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10.1002/cphy.c160034 68
NAD + has an essential role as a source of ADP-ribose for three main classes of enzymes, each releasing nicotinamide as a byproduct: 1) mono- and poly-ADP-ribosyltransferases (ARTs, formerly PARPs) utilize ADP-ribose to modify proteins post-translationally and get activated during DNA repair processes 8
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Our group conducted a review of peptide drug studies focused on targeting PPIs, including MDM2/p53, Keap1/Nrf2, and PD-1/PD-L1
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And, it decreases glucagon secretion in the body
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