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B is needed for the production of neurotransmitters such as GABA, serotonin, and dopamine, and for glycogen breakdown and hemoglobin synthesis
This early appetite effect does not mean the full therapeutic benefit has kicked in
This increase in DAT function stems at least in part from augmented DAT surface expression, pointing to DAT trafficking as the underlying mechanism by which GLP-1R signaling and AA levels controls DA homeostasis in the LS, as depicted by our schematic model (Supplementary Figure 5)
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