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Furthermore, there is a correlation between improvements in sperm count and concentration and weight loss linked to GLP-1RA usage
10.1039/C8MT00142A 67 WangL.HarrisS
China Leads Market Growth with Rapid Treatment Adoption Revenue from obesity GLP-1 treatment in China is projected to exhibit strong growth with a CAGR of 25.4% through 2035, driven by rapidly increasing obesity rates in urban populations and growing consumer demand for weight management solutions

Eligibility criteria for NHS-funded GLP-1 treatment for weight management include: For semaglutide (Wegovy): BMI 35 kg/m (or 32.5 kg/m for people from South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean backgrounds) with at least one weight-related comorbidity For liraglutide (Saxenda): Similar BMI criteria as defined in NICE TA664 Evidence of previous weight management attempts through lifestyle modification Treatment must be initiated within specialist weight management services (Tier 3) Time-limited use as specified in the relevant NICE guidance The referral pathway typically involves: Initial GP consultation: Discuss weight concerns, document BMI and comorbidities, and review previous weight management efforts Tier 2/3 weight management services: Many areas require participation in structured lifestyle programmes before pharmacological intervention Specialist assessment: Referral to specialist weight management services for treatment initiation Ongoing monitoring: Regular review to assess response, tolerability, and continuation criteria Treatment continuation requires achieving the weight loss thresholds specified in the product-specific NICE guidance and SmPCs

L., Parthsarathy, V., Faivre, E